Like synthetic penicillin, the harder the A-Bomb was to make, the more attractive it was to the OSRD

Late in 1942, Britain's highest political, military and Intelligence leadership decided that the Atomic Bomb was almost certainly too difficult and too expensive for Hitler's Germany to produce during World War II ---- if only because it would take too many resources from more pressing necessities for the Nazi war machine.

Howard Florey sole hero of 1944 American national radio play on Penicillin

Here, Howard Florey rules !

Du Pont's Cavalcade of America  on NBC was a very well financed American national radio and later tv show, popular before and after WWII (1935-1957), that as Marcel Lafollette points out , often featured heroes from medicine and science.

Not surprising then that the series featured an half hour show on "The Story of Penicillin" as soon as the censors would let it : which interestingly enough was April 24th 1944  --- starring Howard Florey as the one-and-only who brought us the miracle of penicillin !

Penicillin : a bunch of biologists who put all their faith in chemistry vs two chemists who put all their faith in biology

In the Alice Through the Looking Glass world of wartime penicillin it should hardly be surprising that about the only strong supporters of natural ,biological, penicillin in the upper echelons of the overall enterprise were two professional chemists : Larry Elder of the American Office for Production Research and Development (the OPRD) and Harry Jephcott of the British drug company, Glaxo.

Or that the group most strongly bewitched by the thought of synthetic penicillin were a bunch of medical doctors with Howard Florey and Alexander Fleming leading the charge (with the OSRD and MRC close behind): the sort of scientists who might have been thought would normally occupy a place at the biological end of  hard science.....

OPRD and Dawson vs OSRD and Florey : social or war penicillin ?

If America was to win the war for the Allies by being becoming a ponderous and relentlessly-slow grinding mill of the gods ( a veritable "Arsenal of Democracy" as President Roosevelt proclaimed) than sometimes Vannevar Bush's OSRD (Office of Scientific Research and Development) worked hard against that objective, never more so than with Penicillin (and DDT).

Was it me who said Peer Review is too often "Lions reviewed by Donkeys" ?

I guess it was.

I mean that all too often 'cutting edge' research  - paradigm-shifting research - will be rejected by normal science reviewers.

Instead, a scholar's work should be posted online and judged, over time, by a jury of all of their peers the whole world around, not just by six anonymous ( and usually over-worked) colleagues.

If it stands up, then, and only then, should it be considered for formal review by a senior journal in their field....

Gradually mass produce natural penicillin, starting in 1940, but ban all mention of the word in newspapers : half way moral approach ?

Producing enough penicillin for all Allied civilians and all Allied soldiers but keeping all word of it out of the newspapers and scientific journals might have been the best possible moral approach on its wartime use.

Chloroquine : hiding one of WWII's most valuable secrets in 'plain sight' : in the scientific literature

To understand how OSRD fumbled the ball on synthetic penicillin but neatly hid the fact with lot of the taxpayers' money, consider the similar case of chloroquine, the best anti-malarial drug of WWII (aside from natural quinine) and a truly horrific example of the stupidity that can result from the excessive secrecy of war science.

Keep something out of the newspapers and it can remain a secret forever - even when it is not : the case of wartime DDT

Hard to explain why both the Germans and the Japanese of WWII failed to make use of DDT to reduce their truly immense manpower losses due to endemic insect borne diseases : its use alone, could have prolonged the war a year or two more.

After all, knowledge of how to make the stuff was in the public domain, and in the open scientific literature, having been synthesized more than seventy(70) years earlier.

Penicillin an excellent war weapon because it was so hard to synth, not in spite of that

An excellent antiseptic like synthetic gramicidin was cheap to make, fast acting, stable and a very effective bacterial killer.

But as a weapon of war, it lacked the ability to remain secret for very long .

Henry Dawson's war aims : "You catch more flies with honey than with vinegar..."

The Allies, convinced their troops lacked the Nazi and Japanese killer instinct, spent most of the war trying to prove Dawson wrong by demonstrating that they could be tougher than tough.

But given their overwhelming advantage in men and material over the Axis, it didn't seemed to be working very fast.

Nova Scotia-born Dr Henry Dawson and the wartime re-invention of a military secret weapon into a widely publicized beacon of hope

I am talking about penicillin of course.

What other artifact of war has so abruptly and so totally changed its character over the course of a war ?

The 180 degree flip of wartime penicillin : from secret weapon of war to public weapon of propaganda

War is not at all like the playing fields of Eton , many reports to the contrary.

Both sides get advance notice of the time, place and nature of the activity in sports - and there is a strictly enforced set of rules.

By contrast, a successful military offensive operation is far more than half won if it is kept secret to the last moment and beyond.

Like Penicillin, DDT was a slow killer, so naturally biologists used to the hitherto rapid biological killers, promptly ignored both

Put a bunch of scientists in a room and get them to bet on a race between a tortoise and a hare and they'll plunk their money on the rabbit every time.

That is one big reason why 'we almost lost DDT and penicillin' , to paraphrase a famous wartime ad from the Ayer agency : a bactericide or insecticide that was slow but steady has no great appeal to your average alpha male scientist......

DDT and the myth of "a product of WWII science"

There is no more tired (or dishonest) a journalistic bromide than the claim that this or that boon to humanity was discovered, invented, developed and produced by WWII scientists.

What actually happened, ninety nine times out of a hundred, is that belatedly some senior military or scientific bureaucrat reluctantly agreed to let some underlings spend money on a 'half-baked' idea that had been discovered or invented years earlier but had seen little commercial success up to now.