Pure Sulfa or Salvarsan drugs were far more toxic than impure crude penicillin : so what was the fuss REALLY about then ?

Before 1945, an entire generation of doctors world wide (except for perhaps a half dozen of them) were more willing to put pure but toxic sulfa or salvarsan drugs into their patients than put impure but non toxic penicillin into them.

I will go further:  an entire generation of doctors were willing to seen letting their patients DIE, rather than be seen by other doctors as putting an impure substance into those dying patients.

How doctors rationalize "uncomfortable" successes : natural penicillin and others

Vaccines, Salvarsan, natural penicillin

Obviously, injecting live germs into someone's bloodstream can be potentially very dangerous.